Children with Dry Skin and Atopic Predisposition: Outcome Measurement with Validated Scores for Atopic Dermatitis
نویسنده
چکیده
Background: Dry skin is a common skin condition in childhood. Few studies exist investigating the influence of daily skin care on dry skin in infants at risk of developing atopic dermatitis (AD). We aimed to assess the effect of skin care on dry skin in this special cohort using validated scores for AD and analysis of skin microtopography. Methods: 43 children were randomized to group 1 (G1) and group 2 (G2) and 22 infants to group 3 (G3). During 16 weeks, G1 and G3 applied daily a plant-based emollient and G2 a petrolatum-based emollient. The core outcome was assessed by Severity Scoring of Atopic Dermatitis (SCORAD) and Patient-Oriented SCORing Atopic Dermatitis (PO-SCORAD). The influence on the parents’ life was evaluated by a questionnaire and microtopography by Visioscan ® VC 98. Results: The SCORAD index declined significantly until week (W) 16 in all groups (p ≤ 0.041). The sleeplessness score analyzed by PO-SCORAD was highly reduced after W12 in G1 and after W16 in G2 (p ≤ Received: August 10, 2015 Accepted after revision: January 24, 2016 Published online: June 8, 2016 Priv.-Doz. Dr. med. Natalie Garcia Bartels Department of Dermatology and Allergy, Clinical Research Center for Hair and Skin Science Charité – Universitätsmedizin Berlin, Charitéplatz 1 DE–10117 Berlin (Germany) E-Mail natalie.garcia-bartels @ charite.de © 2016 S. Karger AG, Basel 1660–5527/16/0293–0148$39.50/0 www.karger.com/spp S.S. and M.S. contributed equally to this paper. D ow nl oa de d by : 54 .7 0. 40 .1 1 1/ 13 /2 01 8 11 :5 7: 22 A M
منابع مشابه
Children with Dry Skin and Atopic Predisposition: Outcome Measurement with Validated Scores for Atopic Dermatitis.
BACKGROUND Dry skin is a common skin condition in childhood. Few studies exist investigating the influence of daily skin care on dry skin in infants at risk of developing atopic dermatitis (AD). We aimed to assess the effect of skin care on dry skin in this special cohort using validated scores for AD and analysis of skin microtopography. METHODS 43 children were randomized to group 1 (G1) an...
متن کاملSpecific IgE to Common Food Allergens in Children with Atopic Dermatitis
Background: Atopic dermatitis is a major public health problem, often starting in early childhood and sometimes followed by other allergic diseases. Although hypersensitivity to foods is assumed to play an essential role in the development of atopic dermatitis in some patients, little is known about common food allergens in Iranian children with atopic dermatitis. Objectives: This study was des...
متن کاملBehavioral characteristics in 3-12 month-old infants with Atopic Dermatitis: A case-control study
Background and aim: Atopic dermatitis (AD) is a chronic disorder that is most common in early childhood. Both immunological and psychological factors are important in AD pathogenesis and should therefore be taken into account. The aim of this study was to compare behavioral characteristics of 30 infants (3-12 month-old) with AD with 40 controls.Materials and Methods: Th...
متن کاملEvaluation of the Frequency of Food Allergens by Skin Prick Test in Children with Atopic Dermatitis
Background: The role of food allergy in atopic dermatitis (AD) is controversial. The aim of this study was to determine the frequency of food allergens in children with AD. Method: Fifty one atopic dermatitis children aged 6 months to 5 years entered our study. The severity of AD was determined by scoring index of AD (SCORAD). Skin prick test (SPT) was done using 15 allergens including the whit...
متن کاملProspective Trial Comparing Topical Steroid Application To Wet Versus Dry Skin In Children With Atopic Dermatitis
PROSPECTIVE TRIAL COMPARING TOPICAL STEROID APPLICATION TO WET VERSUS DRY SKIN IN CHILDREN WITH ATOPIC DERMATITIS. Lucinda S. Liu, Yanna Kang, and Richard J. Antaya. Department of Dermatology, Yale University School of Medicine, New Haven, CT. The aim of this study was to determine whether “soak and smear,” a technique where hydration via a 10-minute soak in lukewarm plain water followed by top...
متن کامل